Search on: RAS PROTEINS 
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Descriptor English:   ras Proteins 
Descriptor Spanish:   Proteínas ras 
Descriptor Portuguese:   Proteínas ras 
Synonyms English:   Gene Products, ras  
Tree Number:   D08.811.277.040.330.300.400.500
D12.644.360.525.500
D12.776.157.325.515.500
D12.776.476.525.500
Definition English:   Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47. 
Indexing Annotation English:   ras derived from "Rat Sarcoma"
See Related English:   Genes, ras
 
History Note English:   95 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   32053 
Unique Identifier:   D018631 

Occurrence in VHL:
 

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